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EBV-miR-BART1-5P activates AMPK/mTOR/HIF1 pathway via a PTEN independent manner to promote glycolysis and angiogenesis in nasopharyngeal carcinoma

The endotoxin, upon reaching the liver, binds to TLR4 and co-receptors CD14 and MD-2 in Kupffer cells, thereby initiating downstream signaling pathways that result in excessive production of pro-inflammatory cytokines such as TNF-, IL-6, and IL-8 (Cho et al., 2018)

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Accordingly, AOXs were explored as a method to delay this ageing process

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