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Proc Natl Acad Sci U S A 101:1081010814

The effect of a combination of antibiotics containing vancomycin, enrofloxacin, florfenicol, and metronidazole at different doses on the gut microbiota of grass carp indicated that at higher doses (at 2 mg/fish/d except for vancomycin at 1 mg/fish/d) increased the abundance of Proteobacteria, while the abundance of Fusobacteria and the genus Cetobacterium was reduced (Sun et al., 2021)

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Moreover, this group exhibited an upregulated proportion of intratumoral IFN- + CD8 + T cells (Fig