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This excessive ROS burden inflicts direct oxidative damage to mitochondrial structures and electron transport chain components in pancreatic -cells, while concurrently disrupting key insulin signaling nodes thereby compromising glucose-stimulated insulin secretion and exacerbating peripheral insulin resistance

In these sensing systems, primarily nanozymes oxidize the peroxide and form OH

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In an open-phase trial, participants with schizophrenia ( N = 7) displayed significantly enhanced accuracy in the One Card Learning Task after 8 weeks of GR (68.5 mol/day) administration (45)

The OS rate was not significantly different between the groups after PSM (P=0.42