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Description

Further demonstrating the therapeutic potential of targeting glycolysis, the natural compound derivative D5, sourced from Radix Aucklandiae, attenuates colitis in mice by impeding the nuclear translocation of PKM2 dimers, thereby suppressing glycolytic flux and Th17 cell differentiation (211)

Radical-robust LiPH8 was also successfully engineered by manipulating the transient radical state of radical-susceptible electron-relay

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doi: 10.1146/annurev-cellbio-100617-062608 310 DanemanRPratA

Funding This study was supported by the Natural Science Foundation of Jiangxi Province (20232BAB216029) and Jiangxi Province Traditional Chinese Medicine Science and Technology Program (2023 A0346)