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Now, lets state some facts: we are trying to recruit people to take part in a research project who manage perfectly well on their three-monthly regime

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Vitamin B12 supplements are available in the form of tablets or liquids that a person can take under the tongue (sublingually)

The methylation cycle stalls, and folate becomes trapped in an unusable statea phenomenon clinically referred to as the "folate trap." Because the body can no longer produce adequate amounts of SAMe, the synthesis of crucial neurotransmitters drops dramatically