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Although these medicines have yielded notable improvements in clinical outcomes, their effectiveness is increasingly hindered by intrinsic pharmacological and biological constraints (Volpedo et al., 2019)

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Evidence obtained by examining the overlap between MBP immunoreactivity and NF200 + - fibers in an ex vivo cerebellar slice system indicates that crude HEM, HeA, and HeS can promote the covering of neuronal fibers with OLs

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