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thereby, the CREB1-NRF2 signaling pathway potentiates the function of MSCs, which was shown to increase their therapeutic potential in a humanized mouse model of graft-versus-host disease [37]

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The transcriptomic analysis indicated that the upregulation of Gsto2 in iSPNs affected redox homeostasis and created a hyperdopaminergic state similar to pre-symptomatic Huntingtons disease

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