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One pilot study evaluated the safety and neuroprotective effects of HG inhalation for ischemic stroke, finding that treatment was not only safe, but that patients who received the therapy showed a reduction in infarction size and improved clinical outcomes compared to the placebo group [40]

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An experiment investigating age-related optic nerve injury revealed that regular aerobic exercise (swimming for 60 min per day, 5 days per week for 6 weeks) led to similar responses to acute ischemia-reperfusion-induced optic nerve injury in older mice (12 months) as compared to non-exercised young mice (3 months) (105)

4.2 Adipose tissue Early studies strongly support that periprostatic adipose tissue, particularly under metabolic syndrome-associated inflammation, is a key player in the development of prostate cancer, through the IGF-1 axis, adipokines, and sex hormones (28, 29)