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This toxic metabolite is immediately conjugated with glutathione to form mercapturic acid, which is then excreted in urine

It does this by causing cell cycle arrest between the Go and S phases, preventing cell proliferation, as well as by inhibiting metastasis by downregulating vimentin

Research demonstrated elevated TRPM4 expression in ox-LDL-treated HCAECs, while TRPM4 knockdown reduced intracellular iron levels and ferroptosis-related protein expression (33)

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